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Latest Articles

3D rendering of protein structures using computer modeling techniques.
Article

Key Techniques in Structural Biology, Their Strengths and Limitations

Structural biology uses a variety of techniques to determine the 3D structures of biomolecules such as proteins, nucleic acids and their complexes. In this article, we consider the key techniques, their role in structural biology, strengths and limitations.
Graphic showing a diverse group of individuals.
Article

Embracing Diversity To Advance Science and Clinical Care

Variation is a powerful force in biology. This article explores the importance of moving away from one-size-fits-all approaches and towards diversifying cell lines and clinical trials.
Returning genetic ancestry results to participants of the Afromexico Genomics Project.
Article

Leveling the Field in Ancient DNA Research

Some stories of history are written in ink, and others are written in nucleotide bases. Ancient DNA (aDNA) analysis – the study of DNA from archaeological or paleontological specimens – is perhaps the closest scientists will ever come to a time machine – a window into the past. In this feature article, we explore how inclusion and representation are critical considerations when we look through that window.
Gloved hand holding a slightly open blood agar Petri dish of bacteria up to a computer screen displaying a protein structure.
Article

Understanding Structural Biology, Its Applications and Creating a Molecular Model

In this article, we consider what structural biology tells us and the techniques used to investigate it, the role of computation and how techniques can be used together to answer questions in a range of application areas.
Human immunodeficiency virus-1 virions in the process of budding from a cultured lymphocyte.
Article

Viral Evolution: Changing Priorities Under Environmental Cues

This article will highlight some of the selective pressures that can shape viral evolution, focusing on human parainfluenza virus (HPIV) and human immunodeficiency virus (HIV).
An illustrator's depiction of science's future.
Article

The Future of Science: Humanity Takes a Front Seat

With the world of science rapidly evolving, and a new year beginning, we look at the trends breaking through right now, asking experts: where is the world of science headed?
A 96-well cell culture plate into which a multichannel pipette is being inserted to withdraw media samples.
Article

How Spent Media Analysis Could Pave the Way to Affordable Alternative Proteins

We spoke to Professor Jenny Nelson and Edward O’Neill to find out how spent media analysis could help to drive down costs and make cell cultured proteins an affordable reality for consumers.
Gloved hands hold an agar dish and a cotton swab. In the background other agar dishes and a test tube rack can be seen.
Article

Cell Culture – Good Practice and Advanced Methods

This article will explore the importance of cell culture quality control and highlight recent developments in this area.
Illustration of a cell culture plate with various organoids linking to the area of the human body they are from.
Article

An Introduction to Organoids, Organoid Creation, Culture and Applications

Organoids have revolutionized biological and medical research and proven to be excellent substitutes for animal models in preclinical studies. Here, we discuss what organoids are and how they have been developed over the years to become popular research tools.
A woman and her grandchild.
Article

Can Our Lifestyle Choices Biologically Impact Our Grandkids?

For years, it was understood that only traits or characteristics encoded in our DNA sequence could be transmitted to our offspring. Now, a growing field of research suggests that the mechanisms by which our genes are regulated can also be passed down, perhaps even to our grandkids.
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