Latest App Notes & Case Studies
App Note / Case Study
Identifying Genetic Drivers of Innate Immunity Using Custom Targeted CRISPR Screens
Using genome-wide CRISPR knockout screens, followed by focused CRISPR screens, researchers at Boehringer Ingelheim probed the gene-phenotype relationship of human monocyte phagocytosis when the cells were challenged with Staphylococcus aureus.
App Note / Case Study
CRISPR Engineered Cells Enable Variant Disease Modeling
Comprehensive disease modeling can be challenging for many labs due to variations in reagents, cell culture conditions, technical inconsistencies across protocols and experiments and bandwidth limitations.
App Note / Case Study
Progress Towards Out-of-the-Box Sub-Cellular Imaging
Single cell analysis in a spatially resolved context is the gateway to deciphering scientific questions in various application areas. Such analysis requires the highest available spatial precision combined with highly sensitive detection.
App Note / Case Study
Conducting Research on Highly Pathogenic Viruses Using Virus Pseudotypes
The threat that emerging viruses pose to human health should not be underestimated. These viruses have acquired the ability to infect humans either due to interspecies transmission or naturally occurring changes in the viral genome.
App Note / Case Study
Cell Painting for Phenotypic Screening
Cell painting is a powerful phenotypic screening method used to gain a deeper understanding of the effects of chemical and genetic perturbagens on cells.
App Note / Case Study
Expansion of Specific Lymphocyte Populations
Expansion of Specific Lymphocyte Populations With 4Cell® Nutri-T Xeno-Free, Serum-Free Medium
The success of CAR T-cell therapy requires efficient expansion of specific subpopulations of patient-derived immune cells.
The success of CAR T-cell therapy requires efficient expansion of specific subpopulations of patient-derived immune cells.
App Note / Case Study
Imaging and AI-Assisted Analysis of Retinal Cell Damage
In conventional widefield imaging, a common issue is out-of-focus blur, especially when imaging thick sections or whole-mounted samples like the retina.
App Note / Case Study
From Mammalian Cell Cultures to Pure Proteins: Reduce Your Cell Harvest Time
For therapeutic applications, it is important that protein production from mammalian cell lines is efficient and pure.
App Note / Case Study
Label-Free Single Cell Proteomics Workflow
Label-Free Single Cell Proteomics Workflow With the CellenONE Platform and the TimsTOF SCP
App Note / Case Study
Are You Compliant When it Comes to Pipetting?
During pharmaceutical development and manufacturing, there is always the question: are you following methods for current good laboratory practice or current good manufacturing practice?
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